Shortcuts -- I don't like to type or click!

Here are some of my favorites:

Ctrl-C = Copy
Ctrl-X = Cut
Ctrl-V = Paste
Ctrl-A = Select All

Windows:
Alt-F4 - Closes an application -- used to close Windows, but doesn't with XP anymore.
Shift-Del - delete, but don't send to the Recycle Bin
Flying Window - D -displays the desktop
Flying Window - E - displays Windows Explorer
Flying Windows - M - minimize all windows
Flying Windows - L - lock the computer

Visual Basic.NET
Ctrl-Space -- type a few letters in of a variable then press Ctrl-Space; it will give you a list to choose from. Alt-rightarrow does the same thing. Press the Tab key to make a selection.